In vitro study
Himalca™ suppress the oxidation of A2E and
it has the cytoprotective effect against oxidative A2E
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Production of oxidized-A2E
depends on UV-irradiction time
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Inhibitory effect of Himalca™
on oxidized-A2E production
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Cytoprotective effect of Himalca™
on oxidized-A2E in ARPE-19 cells.
[Nutr Res Pract. 2020 June;14(3):203-217.]
Himalca™ and Asiaticoside inhibit the accumulation of
oxidized A2E and increase cell viability in ARPE19 cells
[Antioxidants (Basel). 2021 Apr 16;10(4):613]
Himalca™ suppressed MNU-induced S phase arrest of cells by inhibiting p21 expression.
[Antioxidants (Basel). 2021 Apr 16;10(4):613]